⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL674966 | 0.73 | — | — | |
| SCHEMBL830748 | 0.72 | POLB (1.00) | — | |
| SCHEMBL3076944 | 0.71 | — | — | |
| SCHEMBL9635561 | 0.71 | — | — | |
| SCHEMBL27547331 | 0.71 | — | — | |
| SCHEMBL13255293 | 0.71 | — | — | |
| SCHEMBL7962385 | 0.69 | POLB (0.93) | — | |
| Ethanesulfonic Acid Amide SCHEMBL9491342 | 0.69 | FFAR3 (0.41) | — | |
| Malonic Acid SCHEMBL28896908 | 0.69 | LDHA (0.64) | — | |
| Succinic Acid SCHEMBL1857902 | 0.69 | LMNA (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174151-B1 | THERAPEUTIC TREATMENT OF EOSINOPHILIA USING CHYMASE INHIBITORS AS THE ACTIVE INGREDIENT | DAIICHI ASUBIO PHARMA CO LTD (JP) | 2007-01-24 | — | — | EP | claimed |
| US-6677344-B2 | Chymase inhibitor for the treatment of eosinophilia | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2004-01-13 | — | — | US | claimed |
| US-6500835-B2 | FOR PROPHYLAXIS AND THERAPY OF FIBROSIS INVOLVING EXTRACELLULAR MATRIX DYSBOLISM HAVING A CHYMASE INHIBITOR AS AN EFFECTIVE INGREDIENT; SIDE EFFECT REDUCTION | SUNTORY LIMITED (JP) | 2002-12-31 | — | — | US | claimed |
| EP-0282079-B1 | COATING COMPOSITION WITH IMPROVED RUST-PREVENTING PROPERTIES FOR USE IN PREPARING LUBRICATED STEEL PRODUCTS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1993-03-03 | — | — | EP | claimed |
| US-4758665-A | Process for preparing high-hiding gamma-modification of unsubstituted linear transquinacridone | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | claimed |
| CN-116075502-B | Antiviral compounds and methods for treating RNA virus (particularly covd-19) infection | 生华生物科技股份有限公司 | 2024-04-12 | — | — | CN | disclosed |
| EP-3280707-B1 | BICYCLIC QUINAZOLINONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2023-12-20 | — | — | EP | disclosed |
| CN-116854681-A | Hormone receptor modulators for the treatment of metabolic conditions and disorders | 阿德利克斯股份有限公司 | 2023-10-10 | — | — | CN | disclosed |
| US-11696911-B2 | Antiviral compounds and method for treating RNA viral infection, particularly COVID-19 | SENHWA BIOSCIENCES, INC. (TW) | 2023-07-11 | — | — | US | disclosed |
| CN-110177783-B | Hormone receptor modulators for the treatment of metabolic conditions and disorders | 阿德利克斯股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-116075502-A | Antiviral compounds and methods for treating RNA virus (particularly covd-19) infection | 生华生物科技股份有限公司 | 2023-05-05 | — | — | CN | disclosed |
| EP-4126846-A1 | ANTIVIRAL COMPOUNDS AND METHOD FOR TREATING HEPATOTROPIC VIRAL INFECTION, PARTICULARLY HEPATITIS B AND HEPATITIS D | Senhwa Biosciences, Inc. (TW) | 2023-02-08 | — | — | EP | disclosed |
| EP-0282079-A2 | Coating composition with improved rust-preventing properties for use in preparing lubricated steel products | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1988-09-14 | — | — | EP | disclosed |
| US-4517133-A | REACTION OF A SULFONYL CHLORIDE WITH AN ISOCYANATE | TEROSON GMBH (DE) | 1985-05-14 | — | — | US | disclosed |
| US-4163797-A | CARBAMOYL OR SULFAMOYL STABILIZER | THE DOW CHEMICAL COMPANY (US) | 1979-08-07 | — | — | US | disclosed |
| US-3960855-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |
| US-3960852-A | BACTERICIDES | SMITHKLINE BECKMAN CORPORATION | 1976-06-01 | — | — | US | disclosed |
| US-3960853-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |
| US-3948905-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |
| US-3939266-A | BACTERICIDE | SMITHKLINE CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |