SCHEMBL30769656

SCHEMBL30769656

Nc1c(F)cnc(Cl)c1[N+](=O)[O-]

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
MAPT P10636 4/20 0.38
HTT P42858 3/20 0.38
LMNA P02545 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HPGD P15428 2/20 0.38
NPC1 O15118 1/20 0.38
TP53 P04637 1/20 0.38
XBP1 P17861 1/20 0.38
RAB9A P51151 1/20 0.38
TLR9 Q9NR96 1/20 0.38
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2372426 1.00 ALDH1A1 (0.40) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL27886417 0.86 ALDH1A1 (0.38) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL6307182 0.81 ALDH1A1 (0.42) ALDH1A1MAPTHTTLMNASMN1; SMN2
SCHEMBL31539735 0.81 GRIN2D (0.41) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL30405501 0.81 ALDH1A1 (0.42) ALDH1A1MAPTHTTLMNASMN1; SMN2
SCHEMBL19814248 0.80 CDK2 (0.49) ALDH1A1MAPTHTTLMNASMN1; SMN2
SCHEMBL25394055 0.79 GRIN2D (0.40) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL14868671 0.79 HSP90AA1 (0.41) ALDH1A1MAPTHTTLMNASMN1; SMN2
SCHEMBL2401652 0.79 CA1 (0.38) ALDH1A1MAPTHTTLMNASMN1; SMN2
SCHEMBL31233522 0.78 PIK3CD (0.38) ALDH1A1MAPTHTTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4558500-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF Sanofi (FR) 2025-05-28 EP disclosed
WO-2024017977-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF SANOFI (FR) 2024-01-25 WO disclosed