SCHEMBL30769811

SCHEMBL30769811

COC1CCCC(c2nc3c(C4CCN(C=O)CC4)ccnc3[nH]2)C1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ PDE4B Q07343 1/20 0.32
▸ PARP1 P09874 1/20 0.31
▸ TLR8 Q9NR97 1/20 0.31
▸ TLR7 Q9NYK1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30769850 0.88 PARP1 (0.41) PARP1TLR8TLR7
SCHEMBL30769756 0.83 PARP1 (0.31) PARP1TLR8TLR7
SCHEMBL27059765 0.80 IRAK4 (0.34) PARP1
SCHEMBL30769742 0.80 IRAK4 (0.34) PARP1
SCHEMBL30769965 0.79 PARP1 (0.37) PARP1
SCHEMBL27056582 0.79 MAPK7 (0.39) —
SCHEMBL30769520 0.79 IRAK4 (0.36) —
SCHEMBL30769800 0.77 IRAK4 (0.33) —
SCHEMBL32664786 0.75 ATR (0.36) PARP1TLR8TLR7
SCHEMBL30769868 0.74 MAPK7 (0.38) PARP1TLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4558500-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF Sanofi (FR) 2025-05-28 — — EP disclosed
WO-2024017977-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF SANOFI (FR) 2024-01-25 — — WO disclosed
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