SCHEMBL30770107

SCHEMBL30770107

CCCCCCC#Cc1c(Br)ccc(Br)c1C#CCCCCCC

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.51
FFAR1 O14842 1/20 0.43
FFAR4 Q5NUL3 1/20 0.43
MMP2 P08253 1/20 0.42
MMP12 P39900 1/20 0.42
GPR84 Q9NQS5 1/20 0.41
PTPN7 P35236 3/20 0.37
HMGCR P04035 1/20 0.37
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2368429 0.91 KCNH2 (0.47) KCNH2FFAR1FFAR4MMP2MMP12
SCHEMBL15287825 0.82 KCNH2 (0.39) KCNH2FFAR1FFAR4MMP2MMP12
SCHEMBL2469973 0.78 KCNH2 (0.46) KCNH2FFAR1FFAR4MMP2MMP12
SCHEMBL9671502 0.78 KCNH2 (0.50) KCNH2FFAR1FFAR4MMP2MMP12
SCHEMBL10794517 0.78 KCNH2 (0.50) KCNH2FFAR1FFAR4MMP2MMP12
SCHEMBL1897376 0.77 FFAR1 (0.55) KCNH2FFAR1FFAR4MMP2MMP12
SCHEMBL6937078 0.77 FFAR1 (0.55) KCNH2FFAR1FFAR4MMP2MMP12
SCHEMBL5886652 0.77 FFAR1 (0.63) KCNH2FFAR1FFAR4MMP2MMP12
SCHEMBL22748252 0.77 FFAR1 (0.48) KCNH2FFAR1FFAR4MMP2MMP12
SCHEMBL22748389 0.77 FFAR1 (0.45) KCNH2FFAR1FFAR4MMP2MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117567234-A Azulene-containing polycyclic aromatic hydrocarbon and preparation method thereof 上海大学 2024-02-20 CN disclosed