SCHEMBL30770435

SCHEMBL30770435

N[S@@](=O)(=NC(=O)Nc1c2c(cc3c1CC3)CCC2)c1sc2c(c1F)CNCC2

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NLRP3 Q96P20 17/20 0.38
PNMT P11086 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22012475 1.00 NLRP3 (0.38) NLRP3PNMT
SCHEMBL30244050 1.00 NLRP3 (0.38) NLRP3PNMT
SCHEMBL30244332 1.00 NLRP3 (0.38) NLRP3PNMT
SCHEMBL30770448 0.85 NLRP3 (0.40) NLRP3
SCHEMBL30243894 0.85 NLRP3 (0.40) NLRP3
SCHEMBL25033931 0.85 NLRP3 (0.40) NLRP3
SCHEMBL30243830 0.85 NLRP3 (0.40) NLRP3
SCHEMBL30243632 0.83 NLRP3 (0.41) NLRP3
SCHEMBL25033898 0.83 NLRP3 (0.41) NLRP3
SCHEMBL30243922 0.83 NLRP3 (0.41) NLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3880659-B1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY NOVARTIS AG (CH) 2024-01-03 EP disclosed