Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 12/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962840 | 1.00 | NLRP3 (0.45) | NLRP3 | |
| SCHEMBL20681349 | 0.89 | NLRP3 (0.47) | NLRP3 | |
| SCHEMBL30244103 | 0.89 | NLRP3 (0.47) | NLRP3 | |
| SCHEMBL30243780 | 0.89 | NLRP3 (0.47) | NLRP3 | |
| SCHEMBL25032674 | 0.89 | NLRP3 (0.48) | NLRP3 | |
| SCHEMBL22012360 | 0.88 | NLRP3 (0.45) | NLRP3 | |
| SCHEMBL21962806 | 0.88 | NLRP3 (0.45) | NLRP3 | |
| SCHEMBL30244082 | 0.88 | NLRP3 (0.45) | NLRP3 | |
| SCHEMBL30770368 | 0.88 | NLRP3 (0.45) | NLRP3 | |
| SCHEMBL30770367 | 0.88 | NLRP3 (0.45) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3880659-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2024-01-03 | — | — | EP | disclosed |