SCHEMBL30770699

SCHEMBL30770699

CC(C)(C)OC(=O)NC(C)(C)c1ccnc(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 15/20 0.46
ATR Q13535 1/20 0.45
SMARCA2 P51531 1/20 0.38
SMARCA4 P51532 1/20 0.38
TRPA1 O75762 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27334225 1.00 AAK1 (0.46) AAK1ATRSMARCA2SMARCA4TRPA1
SCHEMBL26639005 0.83 SMARCA2 (0.44) SMARCA2SMARCA4
SCHEMBL26785544 0.81 STK17B (0.39) AAK1ATR
SCHEMBL30274962 0.80 ACACB (0.46) AAK1ATR
SCHEMBL31412374 0.78 AAK1 (0.42) AAK1
SCHEMBL26791515 0.78 SMN1; SMN2 (0.46) AAK1
SCHEMBL31247637 0.78 GAA (0.43) AAK1ATRTRPA1
SCHEMBL1501665 0.76 SMARCA2 (0.57) ATRSMARCA2SMARCA4
SCHEMBL17040766 0.75 SSTR4 (0.40) AAK1
SCHEMBL1141857 0.75 TRPA1 (0.39) AAK1ATRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 WO disclosed
WO-2024003773-A1 2,7-NAPHTHYRIDINE COMPOUNDS AS MASTL INHIBITORS PFIZER INC. (US) 2024-01-04 WO disclosed