Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL568309 | 1.00 | ATM (0.45) | ATMARKDM1AHDAC1HDAC6 | |
| Bromide SCHEMBL27949951 | 0.98 | ATM (0.44) | ATMARKDM1AHDAC1HDAC6 | |
| SCHEMBL17441422 | 0.86 | HPGD (0.47) | ARKDM1AHDAC1HDAC6MEN1 | |
| SCHEMBL1886206 | 0.83 | GSK3B (0.48) | ARKDM1AHDAC1HDAC6MAPT | |
| SCHEMBL30935127 | 0.83 | GSK3B (0.48) | ARKDM1AHDAC1HDAC6MAPT | |
| SCHEMBL1890248 | 0.81 | ACHE (0.41) | ARKDM1AHDAC1HDAC6MEN1 | |
| SCHEMBL3466469 | 0.81 | AR (0.38) | ARKDM1AHDAC1HDAC6MAPT | |
| SCHEMBL27827224 | 0.79 | AR (0.40) | ARKDM1AHDAC1HDAC6SMN1; SMN2 | |
| SCHEMBL362870 | 0.79 | UHRF1 (0.43) | ATMHDAC1HDAC6MEN1KMT2A | |
| SCHEMBL2799836 | 0.79 | KCNK3 (0.48) | ATMMEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024003773-A1 | 2,7-NAPHTHYRIDINE COMPOUNDS AS MASTL INHIBITORS | PFIZER INC. (US) | 2024-01-04 | — | — | WO | disclosed |