Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25166563 | 1.00 | GAA (0.38) | GAAMAPT | |
| SCHEMBL12879243 | 0.77 | ALDH1A1 (0.30) | — | |
| SCHEMBL13395581 | 0.76 | GAA (0.32) | GAAMAPT | |
| SCHEMBL20355024 | 0.72 | KDM4E (0.40) | GAAMAPT | |
| SCHEMBL30177616 | 0.69 | MEN1 (0.38) | MAPT | |
| SCHEMBL3342338 | 0.69 | MEN1 (0.38) | MAPT | |
| SCHEMBL1752066 | 0.69 | AHR (0.48) | — | |
| SCHEMBL16798562 | 0.69 | ADORA2A (0.38) | — | |
| SCHEMBL16798646 | 0.69 | ADORA2A (0.30) | — | |
| SCHEMBL25082874 | 0.69 | ADORA2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4561563-A2 | TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | Ensem Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026129-A2 | TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |