SCHEMBL30772007

SCHEMBL30772007

CC(C)(C)[C@H](N)C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](CO)c1ccc(-c2ccccc2Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
VHL P40337 16/20 0.44
DPP4 P27487 3/20 0.39
DPP7 Q9UHL4 1/20 0.39
ELOC Q15369 2/20 0.39
ELOB Q15370 2/20 0.39
CFD P00746 1/20 0.38
DPP8 Q6V1X1 2/20 0.38
DPP9 Q86TI2 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27359569 0.90 VHL (0.44) VHLDPP4DPP7ELOCELOB
SCHEMBL30148979 0.90 VHL (0.51) VHLDPP4DPP7ELOCELOB
SCHEMBL26648469 0.88 VHL (0.44) VHLDPP4ELOCELOBCFD
SCHEMBL26648479 0.88 VHL (0.44) VHLDPP4ELOCELOBCFD
SCHEMBL26648474 0.88 VHL (0.44) VHLDPP4ELOCELOBCFD
SCHEMBL30772018 0.88 VHL (0.51) VHLELOCELOB
SCHEMBL30772042 0.86 VHL (0.41) VHLDPP4DPP7ELOCELOB
SCHEMBL30772051 0.85 POLB (0.45) VHLCFD
SCHEMBL24757103 0.84 VHL (0.44) VHLDPP4ELOCELOBCFD
SCHEMBL26648278 0.84 VHL (0.42) VHLDPP4ELOCELOBCFD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024001839-A1 HETEROAROMATIC RING COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2024-01-04 WO disclosed