SCHEMBL30772018

SCHEMBL30772018

CC(C)(C)[C@H](NC(=O)O)C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](CO)c1ccc(-c2ccccc2Cl)cc1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
VHL P40337 20/20 0.51
ELOC Q15369 12/20 0.46
ELOB Q15370 12/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26648523 0.89 VHL (0.52) VHLELOCELOB
SCHEMBL26648535 0.89 VHL (0.52) VHLELOCELOB
SCHEMBL26648531 0.89 VHL (0.52) VHLELOCELOB
SCHEMBL30772007 0.88 VHL (0.44) VHLELOCELOB
SCHEMBL30772051 0.84 POLB (0.45) VHL
SCHEMBL26648612 0.83 VHL (0.51) VHLELOCELOB
SCHEMBL26648609 0.83 VHL (0.51) VHLELOCELOB
SCHEMBL26648616 0.83 VHL (0.51) VHLELOCELOB
SCHEMBL25261054 0.82 VHL (0.74) VHLELOCELOB
SCHEMBL18530418 0.82 VHL (0.74) VHLELOCELOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024001839-A1 HETEROAROMATIC RING COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2024-01-04 WO disclosed