SCHEMBL30772016

SCHEMBL30772016

CC(C)(C)[C@H](N)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc2cc(Cl)ccc2c1

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
VHL P40337 18/20 0.46
ELOC Q15369 11/20 0.46
ELOB Q15370 11/20 0.46
F2 P00734 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30772005 0.91 CFD (0.49) VHLELOCELOB
SCHEMBL18319585 0.90 VHL (0.51) VHLELOCELOB
SCHEMBL17952481 0.90 VHL (0.51) VHLELOCELOB
Hydrochloric Acid SCHEMBL17941139 0.89 VHL (0.51) VHLELOCELOB
Hydrochloric Acid SCHEMBL17941140 0.89 VHL (0.51) VHLELOCELOB
SCHEMBL30772000 0.89 VHL (0.47) VHLELOCELOB
SCHEMBL30772031 0.86 VHL (0.45) VHLELOCELOB
SCHEMBL30772103 0.84 VHL (0.51) VHLELOCELOB
SCHEMBL25616287 0.83 VHL (0.52) VHLELOCELOB
SCHEMBL24333901 0.82 VHL (0.54) VHLELOCELOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024001839-A1 HETEROAROMATIC RING COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2024-01-04 WO disclosed