SCHEMBL30772437

SCHEMBL30772437

Oc1ccc(O)c(-c2cccc3ccccc23)c1-c1cccc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.56
PTPN22 Q9Y2R2 1/20 0.52
MCL1 Q07820 1/20 0.50
ACMSD Q8TDX5 1/20 0.50
NSD2 O96028 1/20 0.49
OPRM1 P35372 1/20 0.49
OPRD1 P41143 1/20 0.49
HKDC1 Q2TB90 1/20 0.49
POLB P06746 1/20 0.48
HSD17B10 Q99714 2/20 0.47
USP2 O75604 1/20 0.47
PAK1 Q13153 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
MAPT P10636 2/20 0.46
MEN1 O00255 1/20 0.46
MAOA P21397 1/20 0.46
KMT2A Q03164 1/20 0.46
IDO1 P14902 1/20 0.46
DHFR P00374 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3915265 0.92 CYP1A2 (0.48) CYP1A2PTPN22MCL1ACMSDNSD2
SCHEMBL29148793 0.92 CYP1A2 (0.48) CYP1A2PTPN22MCL1ACMSDNSD2
SCHEMBL29360295 0.91 NSD2 (0.54) CYP1A2PTPN22MCL1ACMSDNSD2
SCHEMBL214870 0.91 NSD2 (0.54) CYP1A2PTPN22MCL1ACMSDNSD2
SCHEMBL631770 0.91 CYP1A2 (0.62) CYP1A2PTPN22MCL1ACMSDNSD2
SCHEMBL29587504 0.91 CYP1A2 (0.62) CYP1A2PTPN22MCL1ACMSDNSD2
SCHEMBL1840829 0.90 NSD2 (0.53) CYP1A2PTPN22MCL1ACMSDNSD2
SCHEMBL31410627 0.90 NSD2 (0.53) CYP1A2PTPN22MCL1ACMSDNSD2
Hydrochloric Acid SCHEMBL31134043 0.90 PTPN22 (0.57) CYP1A2PTPN22MCL1ACMSDNSD2
SCHEMBL9060865 0.90 NSD2 (0.53) CYP1A2PTPN22MCL1ACMSDNSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113143558-B Removable cover for drug releasing medical device W.L.戈尔及同仁股份有限公司 2024-07-19 CN disclosed
CN-115557835-B Crystal form of vitamin K2, preparation method and application 安徽先和医药研究有限公司 2024-01-05 CN disclosed