Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.53 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29492615 | 1.00 | NSD2 (0.53) | NSD2OPRM1OPRD1HKDC1PTPN22 | |
| SCHEMBL214870 | 0.98 | NSD2 (0.54) | NSD2OPRM1OPRD1HKDC1PTPN22 | |
| SCHEMBL29360295 | 0.98 | NSD2 (0.54) | NSD2OPRM1OPRD1HKDC1PTPN22 | |
| SCHEMBL31410627 | 0.96 | NSD2 (0.53) | NSD2OPRM1OPRD1HKDC1PTPN22 | |
| Hydrochloric Acid SCHEMBL31134043 | 0.96 | PTPN22 (0.57) | NSD2OPRM1OPRD1HKDC1PTPN22 | |
| SCHEMBL9060865 | 0.96 | NSD2 (0.53) | NSD2OPRM1OPRD1HKDC1PTPN22 | |
| Hydrochloric Acid SCHEMBL29492626 | 0.94 | NSD2 (0.51) | NSD2OPRM1OPRD1HKDC1PTPN22 | |
| SCHEMBL5181906 | 0.94 | NSD2 (0.51) | NSD2OPRM1OPRD1HKDC1PTPN22 | |
| Lithium Ion SCHEMBL7651479 | 0.92 | NSD2 (0.50) | NSD2OPRM1OPRD1HKDC1PTPN22 | |
| Hydroxyamine SCHEMBL28598930 | 0.92 | NSD2 (0.50) | NSD2OPRM1OPRD1HKDC1PTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701642-B2 | Method for producing optically active 5-hydroxy-3-ketoester | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-07-11 | — | — | US | claimed |
| CN-104788462-B | Chiral polysubstituted 4-hydroxychroman compound, and preparation method and application thereof | 中国科学院化学研究所 | 2017-02-08 | — | — | CN | claimed |
| US-20160185734-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 5-HYDROXY-3-KETOESTER | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-06-30 | — | — | US | claimed |
| CN-104788462-A | Chiral polysubstituted 4-hydroxychroman compound, and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2015-07-22 | — | — | CN | claimed |
| EP-1466905-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE OXOHEPTENOIC ACID ESTER | NISSAN CHEMICAL IND LTD (JP) | 2011-05-18 | — | — | EP | claimed |
| US-7064209-B2 | Process for producing optically active oxoheptenoic acid ester | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2006-06-20 | — | — | US | claimed |
| EP-0982285-B1 | Optically active halobutenediol ethers and dihydroxy ketones and methods for their preparation | CENTRAL GLASS CO LTD (JP) | 2005-11-02 | — | — | EP | claimed |
| US-20050054853-A1 | Process for producing optically active oxoheptenoic acid ester | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-03-10 | — | — | US | claimed |
| EP-1466905-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE OXOHEPTENOIC ACID ESTER | Nissan Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | claimed |
| US-6326520-B1 | REACTING HALOGENATED ACETALDEHYDE WITH IN PRESENCE OF BINAPHTHOL-TITANIUM COMPLEX | CENTRAL GLASS COMPANY, LIMITED (JP) | 2001-12-04 | — | — | US | claimed |
| EP-0982285-A1 | Optically active halobutenediol ethers and dihydroxy ketones and methods for their preparation | Central Glass Company, Limited (JP) | 2000-03-01 | — | — | EP | claimed |
| EP-0614871-B1 | Process for producing optically active beta-hydroxyketone | TAKASAGO PERFUMERY CO LTD (JP) | 1998-06-10 | — | — | EP | claimed |
| US-5434289-A | Process for producing optically active β-hydroxyketone | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-07-18 | — | — | US | claimed |
| EP-0494771-B1 | Process for producing optically active dihydropyran derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 1995-04-05 | — | — | EP | claimed |
| EP-0614871-A1 | Process for producing optically active beta-hydroxyketone | Takasago International Corporation (JP) | 1994-09-14 | — | — | EP | claimed |
| EP-0353053-B1 | Catalytic process for producing optically active alpha-hydroxycarboxylates | TAKASAGO PERFUMERY CO LTD (JP) | 1993-10-20 | — | — | EP | claimed |
| US-5155240-A | Process for producing optically active dihydropyran derivative | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-10-13 | — | — | US | claimed |
| EP-0494771-A1 | Process for producing optically active dihydropyran derivatives | Takasago International Corporation (JP) | 1992-07-15 | — | — | EP | claimed |
| US-4965398-A | Process for producing optically active alpha-hydroxycarboxylates | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1990-10-23 | — | — | US | claimed |
| EP-0353053-A2 | Catalytic process for producing optically active alpha-hydroxycarboxylates | Takasago International Corporation (JP) | 1990-01-31 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185734-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 5-HYDROXY-3-KETOESTER | CYP51A1, HSD3B1, CYP3A5 | NSD2 4247/4885OPRM1 1512/4885OPRD1 628/4885 |
| US-20050054853-A1 | Process for producing optically active oxoheptenoic acid ester | SQLE, APEH, THOP1 | NSD2 4509/4885OPRM1 903/4885OPRD1 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.