SCHEMBL30772930

SCHEMBL30772930

CC(C)C[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 4/20 0.45
▸ NPY1R P25929 3/20 0.45
▸ NPY2R P49146 3/20 0.45
▸ NTSR2 O95665 2/20 0.41
▸ NTSR1 P30989 2/20 0.41
▸ CCNA2 P20248 2/20 0.40
▸ CDK2 P24941 2/20 0.40
▸ CCNA1 P78396 2/20 0.40
▸ OPRK1 P41145 2/20 0.40
▸ GHSR Q92847 1/20 0.39
▸ BACE1 P56817 3/20 0.39
▸ SLC15A2 Q16348 1/20 0.38
▸ ERAP2 Q6P179 1/20 0.38
▸ ERAP1 Q9NZ08 1/20 0.38
▸ LNPEP Q9UIQ6 1/20 0.38
▸ NPY5R Q15761 2/20 0.38
▸ EGFR P00533 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31188427 0.94 SLC15A2 (0.40) NPY4RNPY1RNPY2RNTSR2NTSR1
SCHEMBL29398799 0.92 CCNA2 (0.44) NPY4RNPY1RNPY2RNTSR2NTSR1
SCHEMBL30462069 0.92 EGFR (0.46) NPY4RNPY1RNPY2RNTSR2NTSR1
SCHEMBL31472853 0.90 NPY4R (0.47) NPY4RNPY1RNPY2RNTSR2NTSR1
SCHEMBL30645270 0.90 NPY4R (0.47) NPY4RNPY1RNPY2RNTSR2NTSR1
SCHEMBL30645273 0.90 NPY4R (0.47) NPY4RNPY1RNPY2RNTSR2NTSR1
SCHEMBL29937022 0.89 ERAP2 (0.47) NPY4RNPY1RNPY2RNTSR2NTSR1
SCHEMBL29937046 0.89 ERAP2 (0.47) NPY4RNPY1RNPY2RNTSR2NTSR1
SCHEMBL29798173 0.89 OPRK1 (0.46) NPY4RNPY1RNPY2RNTSR2NTSR1
SCHEMBL31188431 0.89 SLC15A2 (0.42) NPY4RNPY1RNPY2RNTSR2NTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547703-A1 AMYLIN RECEPTOR (HAMY3R) AGONISTS WITH IMPROVED CHEMICAL STABILITY Gubra A/S (DK) 2025-05-07 — — EP disclosed
WO-2024003359-A1 AMYLIN RECEPTOR (hAMY3R) AGONISTS WITH IMPROVED CHEMICAL STABILITY Gubra A/S (DK) 2024-01-04 — — WO disclosed
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