SCHEMBL3077299

SCHEMBL3077299

Brc1ccn2nccc2c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN5A Q14524 1/20 0.42
AHR P35869 2/20 0.37
PIK3CD O00329 2/20 0.33
DYRK1A Q13627 1/20 0.33
CYP11B1 P15538 1/20 0.33
ADRA2C P18825 1/20 0.33
CYP11B2 P19099 1/20 0.33
DRD4 P21917 3/20 0.32
DRD3 P35462 3/20 0.32
ESR1 P03372 1/20 0.32
RIPK1 Q13546 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
HTT P42858 1/20 0.31
AXL P30530 1/20 0.31
DRD2 P14416 2/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
NAMPT P43490 1/20 0.30
DRD1 P21728 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3064096 0.74 SCN5A (0.42) SCN5APIK3CDDYRK1ACYP11B1CYP11B2
SCHEMBL12489513 0.74 SCN5A (0.42) SCN5APIK3CDDYRK1ACYP11B1CYP11B2
SCHEMBL3089077 0.74 SCN5A (0.42) SCN5APIK3CDDYRK1ACYP11B1CYP11B2
SCHEMBL3076621 0.74 SCN5A (0.42) SCN5APIK3CDDYRK1ADRD4DRD3
SCHEMBL24449040 0.74 SCN5A (0.42) SCN5APIK3CDDYRK1ADRD4DRD3
SCHEMBL24215352 0.74 SCN5A (0.40) SCN5APIK3CDDYRK1ADRD4DRD3
SCHEMBL13212874 0.71 SCN5A (0.59) SCN5APIK3CDCYP11B1CYP11B2
SCHEMBL28275420 0.70 MAP4K4 (0.35) AHRCYP1A2CYP2C19HTTNPC1
SCHEMBL12603995 0.69 SCN5A (0.43) SCN5APIK3CDDRD4DRD3ESR1
SCHEMBL24782798 0.69 SCN5A (0.40) SCN5APIK3CDESR1RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026098632-A1 HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF 江苏恒瑞医药股份有限公司 2026-05-15 WO disclosed
EP-4741391-A1 NMT INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF Nanjing Synnocare Pharmaceutical Technology Co., Ltd. (CN) 2026-05-13 EP disclosed
EP-4737449-A1 P53-Y220C SELECTIVE SMALL-MOLECULAR REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF Changchun Genescience Pharmaceutical Co., Ltd. (CN) 2026-05-06 EP disclosed
EP-4727940-A1 DIHYDROPYRIMIDINE-2, 4 (1H, 3H) -DIONE-CONTAINING POLYCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREOF AND USE THEREOF Linkcure Therapeutics (KY) 2026-04-22 EP disclosed
EP-4716532-A2 BICYCLIC HETEROARYL COMPOUNDS Quantx Biosciences US, Inc. (US) 2026-04-01 EP disclosed
US-20260049080-A1 WILD TYPE KIT INHIBITORS BLUEPRINT MEDICINES CORP (US) 2026-02-19 US disclosed
EP-4262788-B1 UREA OREXIN RECEPTOR AGONISTS MERCK SHARP & DOHME LLC (US) 2026-01-21 EP disclosed
US-12522595-B2 Bicyclic ether O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranosidase inhibitors BIOGEN MA INC. (US) 2026-01-13 US disclosed
EP-4658656-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES Beone Medicines I GmbH (CH) 2025-12-10 EP disclosed
US-20250346597-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEONE MEDICINES I GMBH (CH) 2025-11-13 US disclosed
WO-2015095767-A1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS AND COMBINATIONS THEREOF 3-V BIOSCIENCES, INC. (US) 2015-06-25 WO disclosed
EP-2870150-A1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS 3-V Biosciences, Inc. (US) 2015-05-13 EP disclosed
WO-2014130375-A1 HETEROAROMATIC COMPOUNDS AS PI3 KINASE MODULATORS CALITOR SCIENCES, LLC (US) 2014-08-28 WO disclosed
US-20140234254-A1 HETEROAROMATIC COMPOUNDS AS PI3 KINASE MODULATORS AND METHODS OF USE SUNSHINE LAKE PHARMA CO., LTD. (CN) 2014-08-21 US disclosed
WO-2014078802-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES IRM LLC (BM) 2014-05-22 WO disclosed
WO-2014008197-A1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS 3-V BIOSCIENCES, INC. (US) 2014-01-09 WO disclosed
WO-2014008197-A1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS 3-V BIOSCIENCES, INC. (US) 2014-01-09 WO disclosed
US-20100226881-A1 PYRAZOLO[1,5-a]PYRIDINES AND THEIR USE IN CANCER THERAPY AUCKLAND UNISERVICES LIMITED (NZ) 2010-09-09 US disclosed
EP-2176260-A1 PYRAZOLO[1,5-A]PYRIDINES AND THEIR USE IN CANCER THERAPY AUCKLAND UNISERVICES LIMITED (NZ) 2010-04-21 EP disclosed
WO-2009008748-A1 PYRAZOLO[1,5-A]PYRIDINES AND THEIR USE IN CANCER THERAPY AUCKLAND UNISERVICES LIMITED (NZ) 2009-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049080-A1 WILD TYPE KIT INHIBITORS KIT, CSNK1A1, CSNK1A1L SCN5A 86/4885AHR 3050/4885PIK3CD 291/4885
US-20100226881-A1 PYRAZOLO[1,5-a]PYRIDINES AND THEIR USE IN CANCER THERAPY TP53, PNPO, DPYD SCN5A 2888/4885AHR 767/4885PIK3CD 1820/4885
US-20250346597-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES DGKG, DGKA, DGKK SCN5A 4747/4885AHR 3105/4885PIK3CD 111/4885
US-20140234254-A1 HETEROAROMATIC COMPOUNDS AS PI3 KINASE MODULATORS AND METHODS OF USE PIK3R1, PIK3R3, AKT3 SCN5A 4513/4885AHR 2404/4885PIK3CD 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.