Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | TLR2 | O60603 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | GRB2 | P62993 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29389331 | 0.95 | CASP3 (0.57) | CASP3TLR2MDM2 | |
| SCHEMBL21738585 | 0.95 | CASP3 (0.57) | CASP3TLR2MDM2 | |
| Hydrochloric Acid SCHEMBL21802658 | 0.94 | CASP3 (0.56) | CASP3TLR2MDM2 | |
| Hydrochloric Acid SCHEMBL21802660 | 0.94 | CASP3 (0.56) | CASP3TLR2MDM2 | |
| SCHEMBL31138047 | 0.94 | TLR2 (0.55) | TLR2PTPN1MDM2GRB2 | |
| SCHEMBL30424779 | 0.94 | TLR2 (0.55) | TLR2PTPN1MDM2GRB2 | |
| SCHEMBL29414974 | 0.94 | TLR2 (0.55) | TLR2PTPN1MDM2GRB2 | |
| SCHEMBL30749154 | 0.94 | TLR2 (0.55) | TLR2PTPN1MDM2GRB2 | |
| SCHEMBL30718910 | 0.93 | TLR2 (0.49) | CASP3TLR2PTPN1MDM2 | |
| SCHEMBL30586942 | 0.91 | CASP3 (0.54) | CASP3TLR2MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110582514-B | Conjugates of plasmin cleavable antibodies against insoluble fibrin with drugs | 国立研究开发法人国立癌症研究中心 | 2024-03-01 | — | — | CN | disclosed |