SCHEMBL30774362

SCHEMBL30774362

N#Cc1ccc(-c2cncc3c2ccn3S(=O)(=O)c2cccc([N+](=O)[O-])c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MET P08581 2/20 0.50
TNFSF11 O14788 2/20 0.47
KMT2A Q03164 3/20 0.43
MAPT P10636 2/20 0.42
MEN1 O00255 1/20 0.42
MAPK1 P28482 1/20 0.42
PIK3C3 Q8NEB9 2/20 0.42
PIK3CD O00329 1/20 0.42
PIK3CA P42336 1/20 0.42
PIK3CB P42338 1/20 0.42
KDM1A O60341 1/20 0.41
HTR6 P50406 2/20 0.41
PPME1 Q9Y570 1/20 0.41
LMNA P02545 1/20 0.40
ALDH1A1 P00352 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
GAA P10253 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774522 0.89 KDM1A (0.45) TNFSF11KMT2AMAPTMEN1PIK3C3
SCHEMBL30774604 0.87 HTR6 (0.46) PIK3C3KDM1AHTR6PPME1
SCHEMBL30774596 0.84 KDM1A (0.51) PIK3C3KDM1AHTR6PPME1CA2
SCHEMBL30774371 0.84 PIK3C3 (0.44) PIK3C3KDM1AHTR6PPME1
SCHEMBL30774571 0.84 PIK3C3 (0.44) PIK3C3KDM1AHTR6
SCHEMBL30774608 0.84 HTR6 (0.50) METPIK3C3KDM1AHTR6
SCHEMBL30774373 0.83 HTR6 (0.55) METKMT2AMEN1PIK3C3KDM1A
SCHEMBL30774381 0.82 PIK3C3 (0.44) PIK3C3KDM1AHTR6LMNAALDH1A1
SCHEMBL30774386 0.82 PIK3C3 (0.44) PIK3C3KDM1AHTR6
SCHEMBL30774504 0.79 SLC22A12 (0.51) PIK3C3KDM1AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 US claimed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 EP claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 US disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 EP disclosed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 MET 660/4885TNFSF11 3039/4885KMT2A 2400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.