SCHEMBL30774568

SCHEMBL30774568

N#CN1CCN(c2cncc3c2OCCN3C(=O)C2CN(Cc3cccc(F)c3)C2)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP30 Q70CQ3 3/20 0.41
▸ ALDH1A1 P00352 5/20 0.40
▸ KDM4E B2RXH2 3/20 0.40
▸ HPGD P15428 1/20 0.40
▸ DRD2 P14416 3/20 0.37
▸ HTR1A P08908 2/20 0.37
▸ DRD4 P21917 2/20 0.37
▸ HTR2A P28223 1/20 0.37
▸ HTR7 P34969 1/20 0.37
▸ DRD3 P35462 1/20 0.37
▸ HTR2B P41595 1/20 0.37
▸ MAOB P27338 1/20 0.36
▸ MEN1 O00255 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ FAAH O00519 1/20 0.36
▸ NAAA Q02083 1/20 0.35
▸ GPR6 P46095 1/20 0.35
▸ NPY2R P49146 1/20 0.35
▸ MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774429 0.91 USP30 (0.39) USP30ALDH1A1KDM4EHPGDMAOB
SCHEMBL30774480 0.88 USP30 (0.39) USP30ALDH1A1KDM4EHPGDMAOB
SCHEMBL30774534 0.84 USP30 (0.41) USP30ALDH1A1KDM4EHPGDMAOB
SCHEMBL30774472 0.84 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDMAOBMEN1
SCHEMBL30774601 0.83 ALDH1A1 (0.38) ALDH1A1KDM4EHPGDDRD2HTR1A
SCHEMBL30774590 0.82 USP30 (0.42) USP30ALDH1A1KDM4EHPGDMAOB
SCHEMBL30774666 0.82 ALDH1A1 (0.37) ALDH1A1KDM4EHPGDDRD2HTR1A
SCHEMBL30774521 0.82 ALDH1A1 (0.38) USP30ALDH1A1KDM4EHPGDMAOB
SCHEMBL31635551 0.78 ALDH1A1 (0.48) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL30774750 0.78 ALDH1A1 (0.48) ALDH1A1KDM4EHPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US claimed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP disclosed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 USP30 728/4885ALDH1A1 610/4885KDM4E 1112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback