Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL554584 | 1.00 | CYP2C19 (0.65) | CYP2C19POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27918536 | 0.94 | CYP2C19 (0.59) | CYP2C19POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29808973 | 0.83 | CYP2C19 (0.69) | CYP2C19POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL505353 | 0.83 | CYP2C19 (0.69) | CYP2C19POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11791067 | 0.83 | ALDH1A1 (0.48) | CYP2C19POLBNPC1ALDH1A1HPGD | |
| SCHEMBL28304609 | 0.83 | POLB (0.50) | CYP2C19POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28118794 | 0.82 | KMT2A (0.56) | CYP2C19POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29437050 | 0.82 | POLB (0.72) | CYP2C19POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11521704 | 0.82 | ALDH1A1 (0.53) | CYP2C19POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6970301 | 0.82 | CYP2C19 (0.67) | CYP2C19POLBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024061371-A1 | ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 广州威诺森医药科技有限公司 | 2024-03-28 | — | — | WO | disclosed |