SCHEMBL30774882

SCHEMBL30774882

N#Cc1ccc(-c2cncc3c2OCCN3C(=O)C2CNC2)cc1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ USP30 Q70CQ3 3/20 0.44
▸ UCHL1 P09936 2/20 0.40
▸ KDM1A O60341 1/20 0.39
▸ CYP11B2 P19099 11/20 0.37
▸ CYP11B1 P15538 9/20 0.37
▸ EGLN1 Q9GZT9 2/20 0.36
▸ SLC22A12 Q96S37 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774886 0.86 USP30 (0.45) USP30UCHL1CYP11B2CYP11B1EGLN1
SCHEMBL30774354 0.84 USP30 (0.43) USP30UCHL1KDM1ASLC22A12
SCHEMBL30774747 0.83 SLC22A12 (0.39) USP30UCHL1CYP11B2CYP11B1SLC22A12
SCHEMBL30774802 0.83 USP30 (0.42) USP30UCHL1CYP11B2CYP11B1
SCHEMBL30774857 0.82 SLC22A12 (0.40) USP30UCHL1KDM1ACYP11B2CYP11B1
SCHEMBL30774432 0.82 USP30 (0.42) USP30UCHL1KDM1ACYP11B2
SCHEMBL30774512 0.81 USP30 (0.45) USP30UCHL1CYP11B2CYP11B1SLC22A12
SCHEMBL30774875 0.81 SLC22A12 (0.39) USP30UCHL1CYP11B2CYP11B1EGLN1
SCHEMBL31635549 0.81 RIPK1 (0.39) USP30UCHL1CYP11B2CYP11B1EGLN1
SCHEMBL30774394 0.80 KDM1A (0.39) KDM1ACYP11B2CYP11B1EGLN1SLC22A12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 — — US disclosed
EP-4574830-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Guangzhou Vinnocent Pharmaceutical Limited (CN) 2025-06-25 — — EP disclosed
WO-2024061371-A1 ANNELATED PYRIDINE STEROID SYNTHETASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州威诺森医药科技有限公司 2024-03-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 USP30 728/4885UCHL1 1728/4885KDM1A 621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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