SCHEMBL30775034

SCHEMBL30775034

Cc1ccc(Oc2ccccc2C(=O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.59
CTNNB1 P35222 1/20 0.56
DHODH Q02127 1/20 0.53
KDM4E B2RXH2 7/20 0.53
HSD17B10 Q99714 5/20 0.53
ALDH1A1 P00352 4/20 0.53
HPGD P15428 4/20 0.53
ESR1 P03372 1/20 0.53
ITGB3 P05106 1/20 0.53
ITGA2B P08514 1/20 0.53
HMGB1 P09429 1/20 0.53
TSHR P16473 1/20 0.53
GGT1 P19440 1/20 0.53
PTGS1 P23219 1/20 0.53
PTGS2 P35354 1/20 0.53
BLM P54132 1/20 0.53
NAPRT Q6XQN6 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
AKR1C3 P42330 1/20 0.51
POLB P06746 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL366 1.00 HTT (0.59) HTTCTNNB1DHODHKDM4EHSD17B10
Bromide SCHEMBL2782643 0.98 HTT (0.57) HTTCTNNB1DHODHKDM4EHSD17B10
SCHEMBL28411450 0.91 CTNNB1 (0.66) HTTCTNNB1KDM4EHSD17B10ALDH1A1
SCHEMBL9252102 0.87 CTNNB1 (0.67) HTTCTNNB1KDM4EHSD17B10ALDH1A1
SCHEMBL1798 0.87 CTNNB1 (0.71) HTTCTNNB1KDM4EHSD17B10ALDH1A1
SCHEMBL11604077 0.86 CTNNB1 (0.51) HTTCTNNB1KDM4EALDH1A1HPGD
SCHEMBL2863787 0.86 HTT (0.69) HTTCTNNB1KDM4EHSD17B10ALDH1A1
Phthalic Acid SCHEMBL10983920 0.85 AKR1C3 (0.59) HTTALDH1A1AKR1C3POLBCYP1A2
SCHEMBL4129945 0.85 CTNNB1 (0.69) HTTCTNNB1KDM4EHSD17B10ALDH1A1
Bicarbonate SCHEMBL21517637 0.85 CTNNB1 (0.69) HTTCTNNB1KDM4EHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118546106-A Phenoxy benzamide derivative containing substituted oxadiazole, preparation method and application thereof 宁夏大学 2024-08-27 CN disclosed
CN-117164517-A Phenoxybenzamide derivative containing substituted pyrazole, preparation method and application thereof 西北农林科技大学 2023-12-05 CN disclosed