SCHEMBL2863787

SCHEMBL2863787

COc1ccc(Oc2ccccc2C(=O)O)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.69
KMT2A Q03164 3/20 0.66
MEN1 O00255 2/20 0.66
KDM4E B2RXH2 4/20 0.59
POLB P06746 1/20 0.59
ALDH1A1 P00352 5/20 0.56
MAPT P10636 1/20 0.56
GAA P10253 1/20 0.56
CTNNB1 P35222 1/20 0.56
USP2 O75604 1/20 0.55
TP53 P04637 1/20 0.55
RAB9A P51151 1/20 0.55
HPGD P15428 3/20 0.54
HSD17B10 Q99714 2/20 0.54
LTA4H P09960 1/20 0.53
ESR1 P03372 1/20 0.53
ITGB3 P05106 1/20 0.53
ITGA2B P08514 1/20 0.53
HMGB1 P09429 1/20 0.53
TSHR P16473 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28411450 0.91 CTNNB1 (0.66) HTTKMT2AMEN1KDM4EPOLB
SCHEMBL13851461 0.88 HTT (0.67) HTTKMT2AMEN1KDM4EPOLB
SCHEMBL9252102 0.87 CTNNB1 (0.67) HTTKMT2AMEN1KDM4EPOLB
SCHEMBL1798 0.87 CTNNB1 (0.71) HTTKMT2AMEN1KDM4EALDH1A1
SCHEMBL30775034 0.86 HTT (0.59) HTTKMT2AMEN1KDM4EPOLB
SCHEMBL366 0.86 HTT (0.59) HTTKMT2AMEN1KDM4EPOLB
SCHEMBL4129945 0.85 CTNNB1 (0.69) HTTKMT2AMEN1KDM4EALDH1A1
SCHEMBL11407865 0.85 CTNNB1 (0.69) HTTKMT2AMEN1KDM4EALDH1A1
SCHEMBL8496446 0.85 CTNNB1 (0.69) HTTKMT2AMEN1KDM4EALDH1A1
Bicarbonate SCHEMBL21517637 0.85 CTNNB1 (0.69) HTTKMT2AMEN1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 US disclosed
EP-4593631-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME Mars, Incorporated (US) 2025-08-06 EP disclosed
CN-119968127-A Animal food compositions with improved palatability and customizable properties and methods of making the same 玛氏公司 2025-05-09 CN disclosed
CN-118546106-A Phenoxy benzamide derivative containing substituted oxadiazole, preparation method and application thereof 宁夏大学 2024-08-27 CN disclosed
WO-2024073025-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-04 WO disclosed
EP-4344552-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-03 EP disclosed
CN-117164517-A Phenoxybenzamide derivative containing substituted pyrazole, preparation method and application thereof 西北农林科技大学 2023-12-05 CN disclosed
EP-3112343-B1 AMIDE DERIVATIVES UNIV TOHOKU (JP) 2023-03-29 EP disclosed
US-11040937-B2 Amide derivative TOHOKU UNIVERSITY (JP) 2021-06-22 US disclosed
CN-106029632-B Amide derivatives 国立大学法人东北大学 2019-06-21 CN disclosed
US-20160368860-A1 AMIDE DERIVATIVE TOHOKU UNIVERSITY (JP) 2016-12-22 US disclosed
CN-106029632-A Amide derivatives 国立大学法人东北大学 2016-10-12 CN disclosed
CN-102083836-B Isosorbide derivatives and their use as flavor modifiers, tastants, and taste enhancers SENOMYX INC 2015-01-28 CN disclosed
US-20130295261-A1 ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS SENOMYX, INC. (US) 2013-11-07 US disclosed
US-8420145-B2 Isosorbide derivatives and their use as flavor modifiers, tastants, and taste enhancers SENOMYX, INC. (US) 2013-04-16 US disclosed
EP-2254891-A2 ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS Senomyx, Inc. (US) 2010-12-01 EP disclosed
WO-2009111447-A2 ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS SENOMYX, INC. (US) 2009-09-11 WO disclosed
US-20090220662-A1 ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS SENOMYX, INC. 2009-09-03 US disclosed
US-6169104-B1 COMPOUNDS BIND TUBULIN AND EXHIBIT ANTI-MITOTIC PROPERTIES; USING SUCH COMPOUNDS TO INHIBIT ABNORMAL CELL MITOSIS AND, IN PARTICULAR, TO INHIBIT TUMOR CELL GROWTH LARGE SCALE BIOLOGY CORPORATION 2001-01-02 US disclosed
US-4094900-A Method of preparing aryloxybenzoic and arylthiobenzoic acids SMITHKLINE CORPORATION (US) 1978-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160368860-A1 AMIDE DERIVATIVE ARG1, PTMS, MLX HTT 2978/4885KMT2A 3416/4885MEN1 237/4885
US-20090220662-A1 ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS TAS2R10, TAS2R41, TAS2R30 HTT 2197/4885KMT2A 3200/4885MEN1 4307/4885
US-11040937-B2 Amide derivative ARG1, PTMS, MLX HTT 2978/4885KMT2A 3416/4885MEN1 237/4885
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME PIGS, TAS2R13, CEL HTT 1286/4885KMT2A 1142/4885MEN1 3411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.