Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241844 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| Emoxypine SCHEMBL21061700 | 0.84 | KDM4E (0.73) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| Emoxypine SCHEMBL195347 | 0.84 | KDM4E (0.72) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| Emoxypine SCHEMBL29362452 | 0.84 | KDM4E (0.72) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| Emoxypine SCHEMBL1373708 | 0.82 | KDM4E (0.69) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| Emoxypine SCHEMBL31074958 | 0.82 | KDM4E (0.69) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| Emoxypine SCHEMBL11089142 | 0.82 | KDM4E (0.69) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL12831698 | 0.80 | KDM4E (0.67) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL9007842 | 0.80 | KDM4E (0.67) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL1237716 | 0.80 | KDM4E (0.67) | ALDH1A1KDM4EHPGDHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315734-B | Substituted 2-azabicyclo [3.1.1] heptane and 2-azabicyclo [3.2.1] octane derivatives as orexin receptor antagonists | 克罗诺斯治疗有限公司 | 2024-03-08 | — | — | CN | disclosed |