Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 17/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1586913 | 1.00 | HCRTR1 (0.49) | HCRTR1HCRTR2KEAP1CYP1A2 | |
| SCHEMBL27870879 | 0.88 | HCRTR1 (0.50) | HCRTR1HCRTR2CYP1A2 | |
| SCHEMBL31707742 | 0.86 | HCRTR1 (0.51) | HCRTR1HCRTR2KEAP1CYP1A2 | |
| SCHEMBL1586788 | 0.86 | HCRTR1 (0.51) | HCRTR1HCRTR2KEAP1CYP1A2 | |
| SCHEMBL27029847 | 0.85 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL16666179 | 0.85 | HCRTR1 (0.48) | HCRTR1HCRTR2CYP1A2 | |
| SCHEMBL29931070 | 0.85 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL12179368 | 0.85 | HCRTR1 (0.51) | HCRTR1HCRTR2CYP1A2 | |
| SCHEMBL19206997 | 0.82 | KEAP1 (0.45) | HCRTR1HCRTR2KEAP1 | |
| SCHEMBL18594640 | 0.81 | HCRTR1 (0.48) | HCRTR1HCRTR2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010922-A | Benzoxazole compounds, pharmaceutical compositions containing same and uses thereof | 株洲千金药业股份有限公司 | 2026-05-12 | — | — | CN | disclosed |
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| EP-4688155-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | Bial-Portela & CA, S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |
| WO-2025023852-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |
| CN-113164458-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-111315734-B | Substituted 2-azabicyclo [3.1.1] heptane and 2-azabicyclo [3.2.1] octane derivatives as orexin receptor antagonists | 克罗诺斯治疗有限公司 | 2024-03-08 | — | — | CN | disclosed |