Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.54 |
| ▸ | DPP4 | P27487 | 2/20 | 0.51 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29351176 | 0.95 | OPRM1 (0.51) | OPRM1DPP4XIAPOPRD1CAPN1 | |
| SCHEMBL30389271 | 0.92 | OPRM1 (0.49) | OPRM1DPP4XIAPOPRD1CAPN1 | |
| SCHEMBL31383711 | 0.91 | OPRM1 (0.50) | OPRM1XIAPOPRD1CAPN1OPRK1 | |
| SCHEMBL31198203 | 0.90 | OPRM1 (0.56) | OPRM1DPP4XIAPRENACE | |
| SCHEMBL29377214 | 0.89 | DPP4 (0.50) | OPRM1DPP4XIAPRENACE | |
| SCHEMBL29573728 | 0.88 | DPP4 (0.51) | OPRM1DPP4XIAPCAPN1CTSB | |
| SCHEMBL29575785 | 0.88 | DPP4 (0.53) | OPRM1DPP4XIAPRENACE | |
| SCHEMBL29350886 | 0.88 | DPP4 (0.49) | OPRM1DPP4XIAPRENACE | |
| SCHEMBL30832896 | 0.88 | OPRM1 (0.47) | OPRM1XIAPRENACEOPRD1 | |
| SCHEMBL29776753 | 0.88 | OPRM1 (0.48) | OPRM1XIAPRENACEOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442594-B1 | BLOCK COPOLYMER FOR OVERCOMING DRUG RESISTANCE OF TUMOURS TO CHEMOTHERAPY, ITS POLYMER-DRUG CONJUGATE, PHARMACEUTICAL COMPOSITION CONTAINING THEM, METHOD OF PREPARATION AND USE THEREOF | USTAV MAKROMOLEKULARNI CHEMIE AV CR V V I (CZ) | 2024-02-07 | — | — | EP | claimed |
| EP-3442594-B1 | BLOCK COPOLYMER FOR OVERCOMING DRUG RESISTANCE OF TUMOURS TO CHEMOTHERAPY, ITS POLYMER-DRUG CONJUGATE, PHARMACEUTICAL COMPOSITION CONTAINING THEM, METHOD OF PREPARATION AND USE THEREOF | USTAV MAKROMOLEKULARNI CHEMIE AV CR V V I (CZ) | 2024-02-07 | — | — | EP | disclosed |