Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.50 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GRK2 | P25098 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23784833 | 1.00 | LMNA (0.50) | LMNATP53THRBSMARCA2SMARCA4 | |
| SCHEMBL23784831 | 1.00 | LMNA (0.50) | LMNATP53THRBSMARCA2SMARCA4 | |
| SCHEMBL23784884 | 1.00 | LMNA (0.50) | LMNATP53THRBSMARCA2SMARCA4 | |
| SCHEMBL23784974 | 0.87 | MAPT (0.51) | LMNATP53THRBSMARCA2SMARCA4 | |
| SCHEMBL23784965 | 0.87 | LMNA (0.62) | LMNATP53THRBSMARCA2SMARCA4 | |
| SCHEMBL21326453 | 0.87 | MAPT (0.51) | LMNATP53THRBSMARCA2SMARCA4 | |
| SCHEMBL23784874 | 0.87 | LMNA (0.62) | LMNATP53THRBSMARCA2SMARCA4 | |
| SCHEMBL23784832 | 0.87 | LMNA (0.62) | LMNATP53THRBSMARCA2SMARCA4 | |
| SCHEMBL23784876 | 0.87 | MAPT (0.51) | LMNATP53THRBSMARCA2SMARCA4 | |
| SCHEMBL30208086 | 0.87 | LMNA (0.62) | LMNATP53THRBSMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355522-A | PKC-theta modulators | 爱智药人工智能有限公司 | 2024-01-05 | — | — | CN | disclosed |