SCHEMBL30775718

SCHEMBL30775718

CC(C)(C)[Si](C)(C)OCCO[C@@]1(O)c2ccccc2O[C@@H](c2ccccc2)[C@H]1O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TOP2A P11388 1/20 0.32
AKR1B1 P15121 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30775717 0.76 CYP2C19 (0.40) AKR1B1
SCHEMBL29164512 0.75 CYP2C19 (0.32)
SCHEMBL30775719 0.70 AKR1B1 (0.39) AKR1B1
SCHEMBL28567531 0.70 EPHX1 (0.35) AKR1B1
SCHEMBL30775724 0.66 TOP2A (0.32) TOP2A
SCHEMBL30775722 0.66 TOP2A (0.32) TOP2A
SCHEMBL31208307 0.62 DUT (0.35)
SCHEMBL15560320 0.62 CYP3A4 (0.35) TOP2A
SCHEMBL15550052 0.62 CYP3A4 (0.35) TOP2A
SCHEMBL3542330 0.62 MEN1 (0.35) TOP2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117658967-A Preparation method of flavan-3, 4-diol derivative 朗华生物科学(深圳)有限公司 2024-03-08 CN disclosed