SCHEMBL30775732

SCHEMBL30775732

O=C1CO[C@H]2CCN(C(=O)N3CC4(CC(Cc5cnc(C(F)(F)F)nc5)C4)C3)C[C@H]2N1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MGLL Q99685 9/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27371968 0.90 MGLL (0.57) MGLL
SCHEMBL30775753 0.90 MGLL (0.50) MGLL
SCHEMBL30775746 0.89 MGLL (0.47) MGLL
SCHEMBL30775819 0.88 MGLL (0.44) MGLL
SCHEMBL30775796 0.87 MGLL (0.53) MGLL
SCHEMBL30775770 0.87 MGLL (0.53) MGLL
SCHEMBL30775752 0.86 MGLL (0.53) MGLL
SCHEMBL30775867 0.86 MGLL (0.49) MGLL
SCHEMBL30775907 0.86 MGLL (0.49) MGLL
SCHEMBL27370970 0.86 MGLL (0.49) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4568972-A1 NEW HETEROCYCLIC COMPOUNDS F. Hoffmann-La Roche AG (CH) 2025-06-18 — — EP claimed
WO-2024033277-A1 NEW HETEROCYCLIC COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2024-02-15 — — WO claimed
EP-4568972-A1 NEW HETEROCYCLIC COMPOUNDS F. Hoffmann-La Roche AG (CH) 2025-06-18 — — EP disclosed
WO-2024033277-A1 NEW HETEROCYCLIC COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2024-02-15 — — WO disclosed
Send feedback