Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30778255 | 0.77 | MAPT (0.45) | MAPTKDM4EALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL29159290 | 0.76 | MAPT (0.53) | MAPTKDM4EALDH1A1TSHRKMT2A | |
| SCHEMBL30778197 | 0.76 | CYP19A1 (0.39) | MAPTCYP19A1NPC1RAB9AKDM4E | |
| SCHEMBL30778221 | 0.72 | MAPT (0.48) | MAPTALDH1A1TP53TSHRTDP1 | |
| SCHEMBL30778219 | 0.71 | MAPT (0.54) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL30778209 | 0.71 | MAPT (0.47) | MAPTCYP19A1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29159304 | 0.71 | MAPT (0.47) | MAPTCYP19A1ALDH1A1TSHRMAOB | |
| SCHEMBL30778246 | 0.71 | MAPT (0.47) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30778253 | 0.71 | MAPT (0.47) | MAPTMMP1MMP9 | |
| SCHEMBL30778256 | 0.71 | MAPT (0.50) | MAPTSMN1; SMN2MEN1KMT2AMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603027-A | Olefin difunctional method and delta-trifluoromethyl ketone product prepared by same | 重庆理工大学 | 2024-02-27 | — | — | CN | disclosed |