Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 3/20 | 0.43 |
| ▸ | HTR1B | P28222 | 3/20 | 0.43 |
| ▸ | HTR1F | P30939 | 2/20 | 0.43 |
| ▸ | QDPR | P09417 | 2/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.37 |
| ▸ | FEN1 | P39748 | 4/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24753853 | 1.00 | HTR1D (0.43) | HTR1DHTR1BHTR1FQDPRALOX5AP | |
| SCHEMBL521037 | 0.84 | HTR1D (0.43) | HTR1DHTR1BHTR1FQDPRALOX5AP | |
| SCHEMBL30059220 | 0.84 | HTR1D (0.39) | HTR1DHTR1BHTR1FKCNH2DRD2 | |
| SCHEMBL24753217 | 0.84 | HTR1D (0.39) | HTR1DHTR1BHTR1FKCNH2DRD2 | |
| SCHEMBL29278431 | 0.82 | HTR1D (0.39) | HTR1DHTR1BHTR1FQDPRALOX5AP | |
| SCHEMBL30058907 | 0.82 | HTR1D (0.39) | HTR1DHTR1BHTR1FQDPRALOX5AP | |
| SCHEMBL24754264 | 0.81 | HTR1F (0.38) | HTR1DHTR1BHTR1FALOX5APFEN1 | |
| SCHEMBL24753203 | 0.81 | FEN1 (0.40) | HTR1DHTR1BHTR1FALOX5APFEN1 | |
| SCHEMBL30057743 | 0.81 | FEN1 (0.40) | HTR1DHTR1BHTR1FALOX5APFEN1 | |
| SCHEMBL30056959 | 0.81 | HTR1F (0.38) | HTR1DHTR1BHTR1FALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117460732-A | Pyrrolopyridone compounds, preparation method and application thereof | 杭州中美华东制药有限公司 | 2024-01-26 | — | — | CN | disclosed |