SCHEMBL30778695

SCHEMBL30778695

O=C(Nc1cccn(C2CC2)c1=O)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30778840 0.98 KIF18A (0.64) KIF18A
SCHEMBL30778892 0.95 KIF18A (0.61) KIF18A
SCHEMBL27354973 0.95 KIF18A (0.70) KIF18A
SCHEMBL30778790 0.94 KIF18A (0.62) KIF18A
SCHEMBL30778787 0.94 KIF18A (0.62) KIF18A
SCHEMBL30778718 0.94 KIF18A (0.63) KIF18A
SCHEMBL30778769 0.93 KIF18A (0.68) KIF18A
SCHEMBL30778786 0.93 KIF18A (0.69) KIF18A
SCHEMBL27355201 0.93 KIF18A (0.69) KIF18A
SCHEMBL30778657 0.92 KIF18A (0.66) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024035950-A1 INHIBITORS OF KIF18A AND USES THEREOF ACCENT THERAPEUTICS, INC. (US) 2024-02-15 — — WO disclosed
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