Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.56 |
| ▸ | CTSC | P53634 | 5/20 | 0.55 |
| ▸ | IL1RN | P18510 | 3/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 4/20 | 0.51 |
| ▸ | MMP9 | P14780 | 3/20 | 0.51 |
| ▸ | MMP8 | P22894 | 3/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | MMP3 | P08254 | 2/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2191649 | 0.96 | ERAP2 (0.53) | ERAP2CTSCIL1RNERAP1MMP1 | |
| SCHEMBL2183463 | 0.92 | CTSC (0.61) | ERAP2CTSCIL1RNERAP1MMP1 | |
| SCHEMBL1652403 | 0.91 | KDM4E (0.58) | ERAP2CTSCIL1RNERAP1ACE | |
| SCHEMBL3187724 | 0.89 | ERAP2 (0.55) | ERAP2CTSCIL1RNERAP1MMP1 | |
| SCHEMBL3187737 | 0.89 | ERAP2 (0.55) | ERAP2CTSCIL1RNERAP1MMP1 | |
| SCHEMBL31483276 | 0.89 | ERAP2 (0.69) | ERAP2ACEKDM4EMEN1LMNA | |
| SCHEMBL1650372 | 0.89 | ERAP2 (0.51) | ERAP2CTSCIL1RNERAP1MMP9 | |
| SCHEMBL29350328 | 0.88 | ERAP2 (0.65) | ERAP2IL1RNERAP1ACEKDM4E | |
| Oglufanide SCHEMBL27879986 | 0.88 | ERAP2 (0.67) | ERAP2ACEKDM4EMEN1LMNA | |
| SCHEMBL2197039 | 0.88 | ERAP2 (0.61) | ERAP2IL1RNERAP1MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |