Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.51 |
| ▸ | CTSC | P53634 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | IL1RN | P18510 | 3/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.47 |
| ▸ | GHSR | Q92847 | 3/20 | 0.46 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3187737 | 0.94 | ERAP2 (0.55) | ERAP2CTSCKDM4EMEN1LMNA | |
| SCHEMBL3187724 | 0.94 | ERAP2 (0.55) | ERAP2CTSCKDM4EMEN1LMNA | |
| SCHEMBL2191649 | 0.93 | ERAP2 (0.53) | ERAP2CTSCKDM4EMEN1LMNA | |
| SCHEMBL1652403 | 0.92 | KDM4E (0.58) | ERAP2CTSCKDM4EMEN1LMNA | |
| SCHEMBL3077916 | 0.89 | ERAP2 (0.56) | ERAP2CTSCKDM4EMEN1LMNA | |
| SCHEMBL2160273 | 0.86 | ERAP2 (0.52) | ERAP2CTSCIL1RNERAP1GHSR | |
| SCHEMBL2183848 | 0.86 | CTSC (0.56) | CTSCKDM4EMEN1LMNAMPO | |
| SCHEMBL30729669 | 0.85 | ERAP2 (0.59) | ERAP2KDM4EMEN1LMNAMPO | |
| SCHEMBL30284429 | 0.85 | ERAP2 (0.64) | ERAP2KDM4EMEN1LMNAMPO | |
| SCHEMBL31611296 | 0.85 | ERAP2 (0.59) | ERAP2KDM4EMEN1LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |