Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 7/20 | 1.00 |
| ▸ | DOT1L | Q8TEK3 | 5/20 | 1.00 |
| ▸ | NNMT | P40261 | 5/20 | 1.00 |
| ▸ | CARM1 | Q86X55 | 5/20 | 1.00 |
| ▸ | SETD7 | Q8WTS6 | 4/20 | 1.00 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 1.00 |
| ▸ | PRMT1 | Q99873 | 3/20 | 1.00 |
| ▸ | PCMT1 | P22061 | 2/20 | 1.00 |
| ▸ | SETD2 | Q9BYW2 | 2/20 | 1.00 |
| ▸ | TRDMT1 | O14717 | 2/20 | 1.00 |
| ▸ | PRMT5 | O14744 | 2/20 | 1.00 |
| ▸ | INMT | O95050 | 2/20 | 1.00 |
| ▸ | METTL3 | Q86U44 | 2/20 | 1.00 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 1.00 |
| ▸ | METTL14 | Q9HCE5 | 2/20 | 1.00 |
| ▸ | RNMT | O43148 | 1/20 | 1.00 |
| ▸ | TPMT | P51580 | 1/20 | 1.00 |
| ▸ | NSD1 | Q96L73 | 1/20 | 1.00 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 1.00 |
| ▸ | FASN | P49327 | 3/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sinefungin SCHEMBL19421010 | 1.00 | NSD2 (1.00) | NSD2DOT1LNNMTCARM1SETD7 | |
| Sinefungin SCHEMBL38665462 | 1.00 | NSD2 (1.00) | NSD2DOT1LNNMTCARM1SETD7 | |
| Sinefungin SCHEMBL10400321 | 1.00 | NSD2 (1.00) | NSD2DOT1LNNMTCARM1SETD7 | |
| Sinefungin SCHEMBL24478706 | 1.00 | NSD2 (1.00) | NSD2DOT1LNNMTCARM1SETD7 | |
| Sinefungin SCHEMBL14174630 | 1.00 | NSD2 (1.00) | NSD2DOT1LNNMTCARM1SETD7 | |
| Sinefungin SCHEMBL23607779 | 1.00 | NSD2 (1.00) | NSD2DOT1LNNMTCARM1SETD7 | |
| Sinefungin SCHEMBL167609 | 1.00 | NSD2 (1.00) | NSD2DOT1LNNMTCARM1SETD7 | |
| Sinefungin SCHEMBL3400839 | 1.00 | NSD2 (1.00) | NSD2DOT1LNNMTCARM1SETD7 | |
| Sinefungin SCHEMBL20992057 | 1.00 | NSD2 (1.00) | NSD2DOT1LNNMTCARM1SETD7 | |
| Sinefungin SCHEMBL19418813 | 1.00 | NSD2 (1.00) | NSD2DOT1LNNMTCARM1SETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12629364-B2 | Methods of treating cancers overexpressing CARM1 with EZH2 inhibitors and platinum-based antineoplastic drugs | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2026-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12629364-B2 | Methods of treating cancers overexpressing CARM1 with EZH2 inhibitors and platinum-based antineoplastic drugs | EZH2, CARM1, PRMT6 | NSD2 36/4885DOT1L 8/4885NNMT 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.