Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.50 |
| ▸ | EIF4H | Q15056 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21644587 | 1.00 | SMN1; SMN2 (0.62) | SMN1; SMN2MAPTKDM4EPABPC1EIF4H | |
| SCHEMBL28409859 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTKDM4EPABPC1EIF4H | |
| SCHEMBL30779622 | 0.86 | LRRK2 (0.48) | SMN1; SMN2L3MBTL1LRRK2 | |
| SCHEMBL30779643 | 0.86 | LRRK2 (0.47) | SMN1; SMN2L3MBTL1LRRK2 | |
| SCHEMBL21644641 | 0.86 | LRRK2 (0.47) | SMN1; SMN2L3MBTL1LRRK2 | |
| SCHEMBL21644624 | 0.86 | LRRK2 (0.48) | SMN1; SMN2L3MBTL1LRRK2 | |
| SCHEMBL21644670 | 0.86 | KMT2A (0.58) | SMN1; SMN2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL21644679 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTMEN1KMT2APOLB | |
| SCHEMBL30779574 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTMEN1KMT2APOLB | |
| SCHEMBL30779626 | 0.86 | KMT2A (0.58) | SMN1; SMN2MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111164074-B | Heat shock protein 90 inhibitors | 台北医学大学 | 2024-02-02 | — | — | CN | disclosed |