Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21644679 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTGALR3RAB9AMEN1 | |
| SCHEMBL28416795 | 0.86 | HTT (0.52) | SMN1; SMN2HTTGALR3RAB9AMEN1 | |
| SCHEMBL30779606 | 0.86 | SMN1; SMN2 (0.62) | SMN1; SMN2MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL21644587 | 0.86 | SMN1; SMN2 (0.62) | SMN1; SMN2MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL30779622 | 0.81 | LRRK2 (0.48) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL21644624 | 0.81 | LRRK2 (0.48) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL21644687 | 0.80 | SGMS2 (0.62) | SMN1; SMN2RAB9AMEN1KMT2AGAA | |
| SCHEMBL30779582 | 0.80 | SGMS2 (0.62) | SMN1; SMN2RAB9AMEN1KMT2AGAA | |
| SCHEMBL21644594 | 0.80 | NPC1 (0.57) | SMN1; SMN2RAB9AMEN1KMT2AGAA | |
| SCHEMBL30779640 | 0.80 | NPC1 (0.57) | SMN1; SMN2RAB9AMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111164074-B | Heat shock protein 90 inhibitors | 台北医学大学 | 2024-02-02 | — | — | CN | disclosed |