Valine

Valine

SCHEMBL3078027

CC(C)[C@H](N)C(=O)O.NNC(=O)O

nearest known ligand 0.75

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.75
SLC1A3 P43003 5/20 0.39
SLC1A2 P43004 5/20 0.39
SLC1A1 P43005 5/20 0.39
DPP4 P27487 1/20 0.39
FAP Q12884 1/20 0.39
DPP8 Q6V1X1 1/20 0.39
DPP9 Q86TI2 1/20 0.39
DPP7 Q9UHL4 1/20 0.39
TP53 P04637 1/20 0.35
LAP3 P28838 1/20 0.33
USP2 O75604 1/20 0.32
SLCO1B1 Q9Y6L6 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valine SCHEMBL4639152 0.88 SLC7A5 (0.71) SLC7A5SLC1A3SLC1A2SLC1A1DPP4
Valine SCHEMBL288203 0.87 SLC7A5 (1.00) SLC7A5SLC1A3SLC1A2SLC1A1DPP4
Valine SCHEMBL2785563 0.87 SLC7A5 (1.00) SLC7A5SLC1A3SLC1A2SLC1A1DPP4
Valine SCHEMBL31618928 0.87
Valine SCHEMBL43678 0.87
Valine SCHEMBL8515 0.87
Valine SCHEMBL8516 0.87
Valine SCHEMBL41225 0.87 SLC7A5 (1.00) SLC7A5SLC1A3SLC1A2SLC1A1DPP4
Valine SCHEMBL1813972 0.87 SLC7A5 (1.00) SLC7A5SLC1A3SLC1A2SLC1A1DPP4
Valine SCHEMBL29523401 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7795465-B2 Method for producing semicarbazones BASF AKTIENGESELLSCHAFT (DE) 2010-09-14 US disclosed
US-20070203356-A1 Method For Producing Semicarbazones BASF AKTIENGESELLSCHAFT (DE) 2007-08-30 US disclosed
EP-0577712-B1 FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES DU PONT (US) 1998-07-29 EP disclosed
EP-0577712-A1 FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-01-12 EP disclosed
WO-1992016515-A1 FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-10-01 WO disclosed
EP-0503798-A1 Fungicidal 4-thixooxazolidin-2-ones and 4-iminooxazolindin-2-ones E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-09-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203356-A1 Method For Producing Semicarbazones CBR3, C5, C1S SLC7A5 818/4885SLC1A3 587/4885SLC1A2 1066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.