Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL3078027 | 0.88 | SLC7A5 (0.75) | SLC7A5SLC1A3SLC1A2SLC1A1DPP4 | |
| Valine SCHEMBL2023839 | 0.86 | SLC7A5 (0.65) | SLC7A5CYP1A2TSHRNFKB1MAOA | |
| Valine SCHEMBL9539760 | 0.86 | SLC7A5 (0.71) | SLC7A5TSHRNFKB1LMNASLC1A3 | |
| Valine SCHEMBL935768 | 0.85 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1DPP4 | |
| Valine SCHEMBL296920 | 0.85 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1DPP4 | |
| Valine SCHEMBL756026 | 0.85 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1DPP4 | |
| Valine SCHEMBL2213629 | 0.85 | SLC7A5 (0.88) | SLC7A5LMNASLC1A3SLC1A2SLC1A1 | |
| Valine SCHEMBL8516 | 0.84 | — | — | |
| Valine SCHEMBL43678 | 0.84 | — | — | |
| Valine SCHEMBL1813972 | 0.84 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1889831-A2 | Diazenedicarboxamides as inhibitors of D-alanine: D-alanine ligase (Ddl) | University of Ljubljana (SI) | 2008-02-20 | — | — | EP | claimed |
| EP-1889831-A2 | Diazenedicarboxamides as inhibitors of D-alanine: D-alanine ligase (Ddl) | University of Ljubljana (SI) | 2008-02-20 | — | — | EP | disclosed |