Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 18/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30780331 | 0.90 | TYK2 (0.36) | TYK2JAK2 | |
| SCHEMBL30780304 | 0.83 | TYK2 (0.43) | TYK2 | |
| SCHEMBL26983754 | 0.83 | TYK2 (0.43) | TYK2 | |
| SCHEMBL30780341 | 0.83 | IRAK4 (0.33) | IRAK4 | |
| SCHEMBL30780336 | 0.81 | TYK2 (0.36) | TYK2JAK2 | |
| SCHEMBL30780345 | 0.78 | TYK2 (0.44) | TYK2JAK2 | |
| SCHEMBL30780424 | 0.76 | TYK2 (0.57) | TYK2 | |
| SCHEMBL30780398 | 0.76 | — | — | |
| SCHEMBL26983752 | 0.76 | TYK2 (0.57) | TYK2 | |
| SCHEMBL30780312 | 0.74 | TYK2 (0.43) | TYK2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551559-A1 | HETEROARYL COMPOUNDS AS INHIBITORS OF TYK2/JAK1, COMPOSITION AND APPLICATION THEREOF | Accro Bioscience (HK) Limited (HK) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010963-A1 | HETEROARYL COMPOUNDS AS INHIBITORS OF TYK2/JAK1, COMPOSITION AND APPLICATION THEREOF | ACCRO BIOSCIENCE (HK) LIMITED (CN) | 2024-01-11 | — | — | WO | disclosed |