Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30780315 | 0.84 | SYK (0.40) | IRAK4 | |
| SCHEMBL26983734 | 0.84 | SYK (0.40) | IRAK4 | |
| SCHEMBL30780305 | 0.83 | TYK2 (0.34) | IRAK4 | |
| SCHEMBL30780442 | 0.75 | TYK2 (0.46) | — | |
| SCHEMBL26983700 | 0.75 | TYK2 (0.46) | — | |
| SCHEMBL30780331 | 0.74 | TYK2 (0.36) | — | |
| SCHEMBL26983760 | 0.72 | SYK (0.39) | — | |
| SCHEMBL30780371 | 0.72 | SYK (0.39) | — | |
| SCHEMBL30780398 | 0.71 | — | — | |
| SCHEMBL26983720 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551559-A1 | HETEROARYL COMPOUNDS AS INHIBITORS OF TYK2/JAK1, COMPOSITION AND APPLICATION THEREOF | Accro Bioscience (HK) Limited (HK) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010963-A1 | HETEROARYL COMPOUNDS AS INHIBITORS OF TYK2/JAK1, COMPOSITION AND APPLICATION THEREOF | ACCRO BIOSCIENCE (HK) LIMITED (CN) | 2024-01-11 | — | — | WO | disclosed |