Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30260564 | 0.83 | LRRK2 (0.56) | LRRK2MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL22191522 | 0.83 | LRRK2 (0.56) | LRRK2MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL20004385 | 0.82 | EGFR (0.71) | LRRK2MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL22470355 | 0.81 | IGF1R (0.48) | LRRK2ALDH1A1KMT2AGAANPSR1 | |
| SCHEMBL22404952 | 0.80 | IGF1R (0.49) | LRRK2EGFRGAAAURKAIGF1R | |
| SCHEMBL15330429 | 0.80 | RAB9A (0.53) | LRRK2MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL11813903 | 0.78 | MAPT (0.83) | LRRK2MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL28220480 | 0.77 | MAPT (0.71) | LRRK2MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL3191755 | 0.75 | MAPT (0.69) | MAPTALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL22453043 | 0.75 | KDM4E (0.57) | MAPTALDH1A1KDM4EKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551559-A1 | HETEROARYL COMPOUNDS AS INHIBITORS OF TYK2/JAK1, COMPOSITION AND APPLICATION THEREOF | Accro Bioscience (HK) Limited (HK) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010963-A1 | HETEROARYL COMPOUNDS AS INHIBITORS OF TYK2/JAK1, COMPOSITION AND APPLICATION THEREOF | ACCRO BIOSCIENCE (HK) LIMITED (CN) | 2024-01-11 | — | — | WO | disclosed |