Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29144749 | 1.00 | PNMT (0.38) | PNMTTP53MAPTALDH1A1HPGD | |
| SCHEMBL1894871 | 0.84 | EPHX1 (0.44) | MEN1KMT2ASIGMAR1EPHX1TAAR1 | |
| SCHEMBL1894105 | 0.83 | CYP2C9 (0.42) | MAPTMEN1KMT2AEPHX1TAAR1 | |
| SCHEMBL29144738 | 0.79 | PPARG (0.43) | MEN1KMT2ASIGMAR1EPHX1TAAR1 | |
| SCHEMBL30780884 | 0.77 | POLB (0.39) | TP53MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL29144734 | 0.77 | POLB (0.39) | TP53MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL15142069 | 0.75 | TAAR1 (0.41) | TP53MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1889811 | 0.74 | MAPT (0.41) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL29144752 | 0.74 | EPHX1 (0.39) | HPGDMEN1KMT2ALMNAEPHX1 | |
| SCHEMBL15141781 | 0.74 | PPARG (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466790-B | Preparation method of alpha-sulfinylated carbonyl compound | 西北师范大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-117466790-A | Preparation method of alpha-sulfinylated carbonyl compound | 西北师范大学 | 2024-01-30 | — | — | CN | disclosed |