Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 17/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27267930 | 1.00 | SCN9A (0.46) | SCN9AFFAR4SCN5A | |
| SCHEMBL9873759 | 0.94 | FFAR4 (0.44) | SCN9AFFAR4 | |
| SCHEMBL23908770 | 0.86 | HTR2C (0.41) | SCN9AFFAR4 | |
| SCHEMBL30140248 | 0.86 | SCN9A (0.41) | SCN9AFFAR4SCN5A | |
| SCHEMBL20354811 | 0.85 | HTR2C (0.41) | SCN9A | |
| SCHEMBL30125960 | 0.84 | SCN9A (0.48) | SCN9A | |
| SCHEMBL24777832 | 0.81 | SCN9A (0.49) | SCN9AFFAR4SCN5A | |
| SCHEMBL5241392 | 0.81 | CNR2 (0.38) | SCN9AFFAR4 | |
| SCHEMBL23909099 | 0.81 | CNR2 (0.38) | SCN9A | |
| SCHEMBL24180204 | 0.80 | HTR2C (0.42) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030651-A1 | GPX4 INHIBITORS AND USE THEREOF | SONATA THERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |