SCHEMBL9873759

SCHEMBL9873759

Nc1cc(OCC2CC2)c(Cl)cc1F

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.44
SCN9A Q15858 15/20 0.43
HTR2A P28223 2/20 0.39
HTR2C P28335 2/20 0.39
HTR2B P41595 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30780907 0.94 SCN9A (0.46) FFAR4SCN9A
SCHEMBL27267930 0.94 SCN9A (0.46) FFAR4SCN9A
SCHEMBL23908770 0.86 HTR2C (0.41) FFAR4SCN9AHTR2CHTR2B
SCHEMBL9373385 0.82 SCN9A (0.39) FFAR4SCN9A
SCHEMBL20354811 0.81 HTR2C (0.41) SCN9AHTR2AHTR2CHTR2B
SCHEMBL23915543 0.81 CNR2 (0.40) FFAR4SCN9AHTR2CHTR2B
SCHEMBL10003961 0.81 CNR2 (0.38) FFAR4SCN9AHTR2CHTR2B
SCHEMBL20201733 0.81 SCN9A (0.46) FFAR4SCN9A
SCHEMBL10577542 0.80 NPC1 (0.34) SCN9AHTR2AHTR2CHTR2B
SCHEMBL10685486 0.80 SCN9A (0.33) FFAR4SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5017213-A Herbicides NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) 1991-05-21 US disclosed
EP-0351641-A1 1-Phenylpyrrole NIHON BAYER AGROCHEM K.K. (JP) 1990-01-24 EP disclosed