Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | G6PD | P11413 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2564423 | 1.00 | MAPT (0.52) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL1771501 | 0.83 | ALDH1A1 (0.68) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10969215 | 0.83 | ALDH1A1 (0.57) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL22000046 | 0.81 | TDP1 (0.51) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2565629 | 0.80 | ALDH1A1 (0.53) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2791295 | 0.80 | ALDH1A1 (0.53) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3824393 | 0.80 | MEN1 (0.44) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL34472753 | 0.79 | CYP3A4 (0.46) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10353102 | 0.79 | CYP1A2 (0.46) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2565945 | 0.79 | ALDH1A1 (0.52) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030651-A1 | GPX4 INHIBITORS AND USE THEREOF | SONATA THERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |