Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30781120 | 0.95 | CYP19A1 (0.52) | ALDH1A1HTTNPSR1L3MBTL1CYP19A1 | |
| SCHEMBL7564197 | 0.95 | CYP19A1 (0.55) | ALDH1A1HTTNPSR1L3MBTL1CYP19A1 | |
| SCHEMBL25313311 | 0.89 | HTT (0.43) | ALDH1A1HTTNPSR1L3MBTL1CYP19A1 | |
| SCHEMBL570064 | 0.83 | TDP1 (0.57) | ALDH1A1HTTCYP19A1MAPTKMT2A | |
| SCHEMBL9234021 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HTTMAPTKMT2AMEN1 | |
| SCHEMBL7563741 | 0.82 | CYP19A1 (0.55) | ALDH1A1NPSR1L3MBTL1CYP19A1MAPT | |
| SCHEMBL730095 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HTTNPSR1L3MBTL1MAPT | |
| SCHEMBL27547838 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HTTMAPTKMT2AMEN1 | |
| SCHEMBL5629080 | 0.80 | MAPT (0.53) | ALDH1A1HTTNPSR1MAPTKMT2A | |
| SCHEMBL7569979 | 0.80 | CYP19A1 (0.52) | ALDH1A1HTTNPSR1L3MBTL1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030651-A1 | GPX4 INHIBITORS AND USE THEREOF | SONATA THERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |