Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17802737 | 0.85 | GABRA1 (0.47) | GABRA1GABRB2TSHRMAPTALDH1A1 | |
| SCHEMBL31662735 | 0.76 | GABRA1 (0.56) | GABRA1GABRB2TSHRMAPTALDH1A1 | |
| SCHEMBL860001 | 0.76 | GABRA1 (0.56) | GABRA1GABRB2TSHRMAPTALDH1A1 | |
| SCHEMBL1161818 | 0.75 | GABRA1 (0.48) | GABRA1GABRB2TSHRMAPTALDH1A1 | |
| SCHEMBL8596834 | 0.74 | GABRA1 (0.46) | GABRA1GABRB2TSHRMAPTALDH1A1 | |
| SCHEMBL8103071 | 0.74 | GABRA1 (0.46) | GABRA1GABRB2TSHRMAPTALDH1A1 | |
| SCHEMBL2416799 | 0.74 | ATM (0.59) | MAPTL3MBTL1ATMKMT2ALMNA | |
| SCHEMBL1856534 | 0.73 | GABRA1 (0.56) | GABRA1GABRB2TSHRMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL8619037 | 0.72 | GABRA1 (0.45) | GABRA1GABRB2TSHRMAPTALDH1A1 | |
| SCHEMBL10515048 | 0.72 | TSHR (0.55) | GABRA1GABRB2TSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030651-A1 | GPX4 INHIBITORS AND USE THEREOF | SONATA THERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |