Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208136 | 1.00 | TSHR (0.53) | TSHRLMNAMEN1HPGDKMT2A | |
| SCHEMBL7700608 | 0.84 | TSHR (0.55) | TSHRLMNAMEN1HPGDKMT2A | |
| SCHEMBL27809344 | 0.82 | TSHR (0.48) | TSHRLMNAMEN1HPGDKMT2A | |
| SCHEMBL1934510 | 0.82 | L3MBTL1 (0.51) | TSHRLMNAMEN1HPGDKMT2A | |
| SCHEMBL254876 | 0.82 | TSHR (0.61) | TSHRLMNAMEN1HPGDKMT2A | |
| SCHEMBL10415892 | 0.81 | TSHR (0.52) | TSHRLMNAMEN1HPGDKMT2A | |
| SCHEMBL20681151 | 0.81 | TSHR (0.52) | TSHRLMNAMEN1HPGDKMT2A | |
| SCHEMBL5243706 | 0.81 | TSHR (0.52) | TSHRLMNAMEN1HPGDKMT2A | |
| SCHEMBL4093002 | 0.81 | TSHR (0.67) | TSHRLMNAMEN1HPGDKMT2A | |
| SCHEMBL1027223 | 0.81 | KMT2A (0.50) | TSHRLMNAMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030651-A1 | GPX4 INHIBITORS AND USE THEREOF | SONATA THERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |