Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 10/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27119337 | 1.00 | USP7 (0.48) | USP7KCNH2USP2ALDH1A1TP53 | |
| SCHEMBL27152123 | 1.00 | USP7 (0.48) | USP7KCNH2USP2ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL27141973 | 0.99 | USP7 (0.48) | USP7KCNH2USP2ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL30781371 | 0.99 | USP7 (0.48) | USP7KCNH2USP2ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL27141976 | 0.99 | USP7 (0.48) | USP7KCNH2USP2ALDH1A1TP53 | |
| SCHEMBL30781218 | 0.91 | USP7 (0.46) | USP7KCNH2KDM1A | |
| SCHEMBL27130717 | 0.91 | USP7 (0.46) | USP7KCNH2KDM1A | |
| Hydrochloric Acid SCHEMBL30781346 | 0.91 | USP7 (0.46) | USP7KCNH2KDM1A | |
| Hydrochloric Acid SCHEMBL27152351 | 0.91 | USP7 (0.46) | USP7KCNH2KDM1A | |
| SCHEMBL30781190 | 0.89 | USP7 (0.59) | USP7KCNH2USP2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024042494-A1 | SUBSTITUTED PYRROLOTRIAZINES | MOLECURE SA (PL) | 2024-02-29 | — | — | WO | claimed |
| WO-2024042494-A1 | SUBSTITUTED PYRROLOTRIAZINES | MOLECURE SA (PL) | 2024-02-29 | — | — | WO | disclosed |